Substituted amine derivatives, their production an

专利名称：Substituted amine derivatives, their

production and use

发明人：Tsushima, Susumu,Takatani, Muneo,Hirata,

Minoru

申请号：EP88300596.9申请日：19880126公开号：EP0278621B1公开日：19910612

摘要：Substituted amino derivatives represented by the formula: wherein R¹ and R²each stand for an acyclic hydrocarbon residue or an alicyclic hydrocarbon residue; R³ andR⁴ each stand for hydrogen or a hydrocarbon residue optionally containing hetero-atom(s); A stands for a carbon chain having two or more carbon atoms optionallycontaining ether linkage or sulfide linkage, which may be substituted and which may perse form a ring; X¹ and X² each stand for oxygen atom or sulfur atom; and Y stands foramino group or an organic residue bonded through nitrogen atom, which may form a ringby combining with a carbon atom constituting A; and their salts have anti-arrhythmicactivity and are useful for prevention and treatment of a variety of arrhythmias.

申请人：TAKEDA CHEMICAL INDUSTRIES, LTD.

地址：1-1, DOSHOMACHI 4-CHOME; CHUO-KU, OSAKA

代理机构：Lewin, John Harvey

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