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MALEIMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS

来源:伴沃教育
专利内容由知识产权出版社提供

专利名称:MALEIMIDE DERIVATIVES,

PHARMACEUTICAL COMPOSITIONS ANDMETHODS FOR TREATMENT OF CANCER

发明人:LI, Chiang J,ASHWELL, Mark Antony,HILL,

Jason,MOUSSA, Magdi M.,MUNSHI, Neru

申请号:EP06720509.6申请日:20060209公开号:EP1846406A1公开日:20071024

摘要:The present invention relates to pyrroloquinolinyl-pyrrole-2,5-dionecompounds and pyrroloquinolinyl-pyrrolidine-2,5-dione compounds, and methods ofpreparation of these compounds. The present invention also relates to pharmaceuticalcompositions comprising pyrroloquinolinyl-pyrrole-2,5-dione compounds andpyrroloquinolinyl-pyrrolidine-2,5-dione compounds. The present invention providesmethods of treating a cell proliferative disorder, such as a cancer, by administering to asubject in need thereof a therapeutically effective amount of a pyrroloquinolinyl-pyrrole-2,5-dione compound or pyrroloquinolinyl-pyrrolidine-2,5-dione compound of the presentinvention.

申请人:ArQule, Inc.

地址:19 Presidential Way Woburn, MA 01801 US

国籍:US

代理机构:UEXKÜLL & STOLBERG

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