COMPOSITIONS AND METHODS FOR TRAPPING AND INACTIVA

专利名称：COMPOSITIONS AND METHODS FOR

TRAPPING AND INACTIVATINGPATHOGENIC MICROBES ANDSPERMATOZOA

发明人：GARG, Sanjay,ZANEVELD, Lourens, Jan,

Dirk,ANDERSON, Robert, Anthony,Jr.,WALLER, Donald, Paul

申请号：EP019101.1申请日：20010306公开号：EP1263411A2公开日：20021211

摘要：Antimicrobial and composition for contraception and method can preventand/or reduce the sexually transmitted disease (STD) propagated by sexuality, andprevent and/or reduce the dangerous offer of pregnancy. The composition contains (1)matrix formers, the bio-adhesive agent of (2), (3) buffer, (4) optional wetting agent, (5)optionally preservative, and (6) water; Wherein the composition is suitable for theapplication of intravaginal; Wherein (thus microorganism and sperm for capturingejaculation release) is projected in the contact of composition form semisolid matrix;Wherein the composition causes cervical mucus to harden (thus reducing a possibility thatsperm enters); Wherein composition forms biological viscosity layer (thus dangerousSTD-causing microorganisms and vagina surface for preventing or reducing contact) invagina surface; Wherein the composition keeps acidic vaginal pH to project in sperm fromabove-mentioned male less than about 5; And wherein the microflora of the unobvious

damage intravaginal of composition balances. Antimicrobial and composition for

contraception can also comprising additional antibacterial and/or contraceptive (such as,nonoxynol-9, octoxynol 9, benzalkonium chloride, the hesperidine of phosphorylation,sulfonation aurantiamarin, polystyrenesulfonate, substituted benzenesulfonic acidformaldehyde copolymer, H2SO4-modified mandelic acids, povidone iodine, Itraconazole,ketoconazole, metronidazole, clotrimazole, Fluconazole, teraconazole, miconazole,Tinidazole, iconazole, chloramphenicol, nystatin, cyclopiroxolamine etc.).

申请人：RUSH-PRESBYTERIAN-ST.LUKE'S MEDICAL CENTRE

地址：1753 West Congress Parkway Chicago, IL 60612-2833 US

国籍：US

代理机构：HOFFMANN - EITLE

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