专利名称：ASSAYS, SYSTEMS, AND METHODS FOR
OBTAINING PERSONALIZED ANABOLICPROFILES
发明人：Monty Montano申请号：US14423013申请日：20130820
公开号：US20150285789A1公开日：20151008
专利附图：
摘要：Disclosed herein are novel assays, systems and kits for generating a
personalized or stratified diagnostic report, e.g., to facilitate selection of an appropriate
treatment of a musculoskeletal disease or disorder in a subject. The assays and systemsare based on detecting and/or measuring in vitro anabolic responses of musculoskeletalcells or precursor cells thereof to a panel of test compositions (e.g., test compositionseach comprising at least one agent selected to maintain and/or increase muscle and/orbone growth), and ranking the ability of each test composition to stimulate muscle andbone growth. The resultant ranks of the test compositions can then be used to identify,select, and/or optimize a treatment regimen for the subject who is determined to have,or have a risk, a musculoskeletal disease or disorder. Methods for treating and/orpreventing a musculoskeletal disease or disorder are also provided herein.
申请人：BOSTON MEDICAL CENTER CORPORATION
地址：Boston MA US
国籍：US
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